Collateral genome instability by DNA damage in mitosis.
نویسندگان
چکیده
SUMMARY Chromosome segregation errors and DNA damage are in a vicious cycle in cancer cells. Bakhoum and colleagues show that the molecular response to damaged DNA during mitosis impairs the chromosome segregation machinery, adding a new level to the already dangerous relations between different kinds of genomic instability.
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عنوان ژورنال:
- Cancer discovery
دوره 4 11 شماره
صفحات -
تاریخ انتشار 2014